25 IS THE OXIDATIVE STRESS ONE OF IVF FAILURE PREDICTORS?

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Impact of oxidative stress on IVF

Stefan S du Plessis, Kartikeya Makker, Nisarg R Desai and Ashok Agarwal† †Author for correspondence Center for Reproductive Medicine, Glickman Urological and Kidney Institute and Ob–Gyn and Women’s Health Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk A19.1, Cleveland, OH 44195, USA Tel.: +1 216 444 9485 Fax: +1 216 445 6049 [email protected] Gametes and embryos are natural sources of free...

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Oxidative stress and heart failure.

Oxidative stress, defined as an excess production of reactive oxygen species (ROS) relative to antioxidant defense, has been shown to play an important role in the pathophysiology of cardiac remodeling and heart failure (HF). It induces subtle changes in intracellular pathways, redox signaling, at lower levels, but causes cellular dysfunction and damage at higher levels. ROS are derived from se...

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Recurrent IVF failure: is third party reproduction the only option?

For many couples experiencing infertility, IVF constitutes the last resort treatment, sometimes after other treatment options have also failed. Unfortunately, IVF is not always successful, and the cause for the implantation failure quite often remains unexplained. Depending on the specific circumstances, the use of donor eggs, donor sperm or even a gestational carrier are often recommended in a...

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Regular Exercise or Food Restriction, Which is Better in the Event of Heart Failure? An Approach to Oxidative Stress and Angiogenesis

The aim of present study was to investigate whether food restriction combined with exercise training could attenuate the oxidative stress and promote angiogenesis in a rat model of heart failure. 50 male wistar rats weighing 250-300 g were randomly divided into 5 groups including: 1) sham; they were fed ad libitum food, n=10. 2) Heart failure group; 3) Exercise group; they run on a treadmill 5 ...

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What Is Oxidative Stress ?

Oxidative stress is well known to be involved in the pathogenesis of lifestyle-related diseases, including atherosclerosis, hypertension, diabetes mellitus, ischemic diseases, and malignancies. Oxidative stress has been defined as harmful because oxygen free radicals attack biological molecules such as lipids, proteins, and DNA. However, oxidative stress also has a useful role in physiologic ad...

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ژورنال

عنوان ژورنال: Reproductive BioMedicine Online

سال: 2010

ISSN: 1472-6483

DOI: 10.1016/s1472-6483(10)62443-1